SEKELA UKULINGANISELA KWAMASELU AMATHAMBO UKUSETSHENZISWA KWEMETABOLISM, KHUTHAZA UKUSEBENZISANA KWESIKHUNGO SAMATHAMBO
Wonke amangqamuzana ohlelweni lokuzivikela komzimba avela emnkantsheni. Izifundo zakamuva zithole ukuthi kukhona ukuxhumana okuseduze phakathi kwamangqamuzana amathambo nokuzivikela komzimba komuntu. Amangqamuzana amathambo angathonya amangqamuzana omzimba, futhi impendulo yokuzivikela komzimba ingaphazamisana nokusetshenziswa kwamathambo. Umnkantshe wakhiwa izicubu ezixhumeneyo ezine-fibrous, imithambo yegazi, imizwa namaseli. Unesibopho sokukhiqizwa kwamangqamuzana ahlukahlukene ahilelekile ekuvikeleni komzimba, okuhlanganisa ama-osteoblast nama-osteoclast, asetshenziselwa ukulawula ukuguquka kwamathambo, kanye namangqamuzana omzimba anjengamaseli amhlophe egazi. Ibhalansi ye-metabolic yama-osteoblast nama-osteoclast ayibalulekile nje kuphela empilweni yamathambo, kodwa futhi ithinta ngqo ukwakheka kwama-leukocyte emnkantsheni.
Ucwaningo lwesayensi lubonisa ukuthi i-collagen peptide inomphumela okhethekile wokukhuthaza umnkantsha wamathambo.
* Ukulawulwa Okulungiselelwe kwe-osteoblast kanye ne-osteoclast metabolism
* Kukhuthaza ukulinganisela kwe-metabolism yamaseli amathambo kanye nokukhiqizwa kwamaseli omzimba
* Sekela ukusebenza okuvamile komnkantsha wamathambo
* Kukhuthaza ukusebenzisana kwamasosha omzimba amathambo
I-peptide ye-Collagenimikhiqizo isekela ukusebenza okuvamile kwesikhumba, i-extracellular matrix kanye nomnkantsha wamathambo, okuye kwafakazelwa ngokwesayensi ukuthi kuyasiza ekulawulweni kwamasosha omzimba womuntu kanye nokuqinisa isisekelo samasosha omzimba womuntu. Njengokudla okusebenzayo okuncane,i-collagenAyinazo izinto ezibangela ukungezwani komzimba futhi ayinaphunga elikhethekile. Iyisengezo sokudla semvelo esifanele sokuthuthukisa amasosha omzimba.
Ama-peptide athile e-collagenous asekela i-metabolism yamaseli ezicutshini ezixhumene futhi alawula kahle i-metabolism ye-fibroblast, ngaleyo ndlela akhuthaze i-biosynthesis yamaprotheni amaningana e-extracellular matrix (kufaka phakathi i-collagen) ahilelekile ekuphenduleni komzimba. I-collagen yohlobo lwe-I iyiprotheni enkulu yesakhiwo emzimbeni enemiphumela yokulawula amasosha omzimba futhi inciphisa ukuvuvukala. Esifundweni sango-2014, abesifazane abangu-114 abaneminyaka engu-45-65 abathola amagremu angu-2.5 ama-peptide athile e-collagen asebenzayo ngosuku amasonto ayisishiyagalombili babonise ukwanda okukhulu kwe-procollagen yohlobo lwe-I.
Isikhathi sokuthunyelwe: Jan-05-2022
