INDABA YOMLANDO WAMAKHAPSULE E-GELATIN
Okokuqala, sonke siyazi ukuthi kunzima ukugwinya izidakamizwa, ngokuvamile zihambisana nephunga elibi noma ukunambitheka okubabayo. Abantu abaningi bavame ukungathandi ukulandela imiyalelo yodokotela babo yokusebenzisa izidakamizwa ngoba izidakamizwa zibaba kakhulu ukuba zingagwinywa, ngaleyo ndlela kuthinte ukusebenza kahle kokwelashwa. Enye inkinga odokotela neziguli ababhekane nayo esikhathini esidlule ukuthi akunakwenzeka ukulinganisa ngokunembile umthamo kanye nokuhlushwa komuthi ngoba ayikho indinganiso efanayo yokulinganisa.
Ngo-1833, usokhemisi osemusha waseFrance, uMothes, wakha ama-capsule athambile e-gelatin. Usebenzisa indlela lapho umthamo othize womuthi ugoqwa ngesisombululo se-gelatin esishisayo esiqina njengoba siphola ukuze sivikele umuthi. Ngesikhathi egwinya i-capsule, isiguli asisenalo ithuba lokunambitha isikhuthazi somuthi. Isithako esisebenzayo somuthi sikhishwa kuphela lapho i-capsule ithathwa ngomlomo emzimbeni futhi igobolondo lincibilika.
Ama-capsule e-Gelatin athandwa kakhulu futhi kwatholakala ukuthi ayi-excipient efanelekile yezokwelapha, njengoba i-gelatin iwukuphela kwento emhlabeni encibilika ekushiseni komzimba. Ngo-1874, uJames Murdock eLondon wakha i-capsule yokuqala ye-gelatin eqinile emhlabeni equkethe i-capsule kanye nomzimba we-capsule. Lokhu kusho ukuthi umenzi angafaka impuphu ngqo ku-capsule.
Ekupheleni kwekhulu le-19, amaMelika ayehola ekuthuthukisweni kwama-capsule e-gelatin. Phakathi kuka-1894 no-1897, inkampani yemithi yaseMelika i-Eli Lilly yakha imboni yayo yokuqala yama-capsule e-gelatin ukukhiqiza uhlobo olusha lwe-capsule enezicucu ezimbili, ezizivalayo.
Ngo-1930, uRobert P. Scherer wasungula umshini wokugcwalisa ozenzakalelayo, oqhubekayo, owenza ukukhiqizwa kwama-capsule ngobuningi kwaba nokwenzeka.
Sekuyiminyaka engaphezu kweyikhulu, i-gelatin ibilokhu iyinto eluhlaza ebaluleke kakhulu ekhethwayo kuma-capsule aqinile nathambile futhi isetshenziswa kabanzi.
Isikhathi sokuthunyelwe: Juni-23-2021
