Ikhaya

 

I-Collageniyisici esiyinhloko se-extracellular matrix (ECM), etholakala ikakhulukazi esikhumbeni somuntu, emathanjeni, e-cartilage, emazinyweni, emisipha, emithanjeni, nasemithanjeni yegazi. Futhi iyiprotheni ebalulekile yesakhiwo sezicubu ezixhumeneyo.

I-Collagen iyisici esiyinhloko se-dermis yesikhumba somuntu. Kanye nenani elincane le-elastin, yakha inethiwekhi evamile yemicu ye-collagen, enikeza isikhumba ukunwebeka nokuqina futhi ivumele ungqimba lwe-epidermal ukuthi luthuthe umswakama.

Kodwa-ke, izici ezifana nokuguga, imisebe ye-UV, ukubhema, kanye nendlela yokuphila engenampilo zibangela ukwehla kwe-collagen. Uma i-collagen ilahleka ngobuningi, izimpawu zokuguga njengokulahlekelwa ukunwebeka kwesikhumba, ukugoba, imibimbi, umbala, ukoma, isikhumba esiqinile, kanye nesikhumba esibucayi ziyavela kancane kancane.

Ngakho-ke, njengoba i-collagen incipha, ingabe imikhiqizo ye-collagen yomlomo ingayibambezela inqubo yokuguga?

Ingabe ama-peptide e-collagen omlomo angamuncwa ngumzimba?

Imikhiqizo evamile ye-collagen emakethe ibhekisela kuma-peptide e-collagen, hhayi i-collagen.

I-CollagenAma-peptide ayingxube yama-peptide anesisindo esiphansi sama-molecule anesisindo sama-molecule esimaphakathi esingu-2000 kuya ku-10,000 Da esifakwe i-hydrolyzed kusuka ku-collagen (300,000 Da). Uma kuqhathaniswa ne-collagen enesisindo sama-molecule amaningi, ama-peptide e-collagen anesisindo esincane sama-molecule futhi agaywa futhi amuncwe kalula.

Ngaphezu kwalokho, ama-dipeptide nama-tripeptide aqukethwe kuma-collagen peptides athuthwa ngqo futhi amuncwe njengama-peptide yi-oligopeptide transporter protein (PepT1) ekhona kumaseli e-epithelial emathunjini amancane. Angaqondiswa ezindaweni ezithile emzimbeni ukuze asebenze kahle futhi asebenze kahle.

UWatanabe-Kamiyama M. nabanye badle ama-peptide e-collagen anelebula lika-14C ezithweni ezahlukene zamagundane futhi babona ukusatshalaliswa kwawoama-peptide e-collagen.

Ucwaningo lubonise ukuthi ama-peptide e-collagen omlomo asatshalaliswa ezithweni ezinkulu kuwo wonke umzimba ngemva kokugaya nokumuncwa, futhi afakwa ngqo ezicutshini ezicebile nge-collagen, ikakhulukazi isikhumba, ngemva kwesikhathi esithile.

Ingabe Ama-Oral Collagen Peptides Angathuthukisa Izimo Zesikhumba?

Eminyakeni yamuva nje, izifundo eziningi ziqinisekisile imiphumela emihle yama-peptide e-collagen oral ekubambezeleni ukuguga kwesikhumba nokuvuselela isikhumba.

Abacwaningi bakhethe abantu abazithandelayo abangu-64 abaneminyaka ephakathi kuka-40 no-60 ubudala ukuthi bathathe ama-1000 mg ama-collagen peptides anesisindo esiphansi sama-molecule ngomlomo nsuku zonke amasonto ayi-12 futhi bathola ukuthi ngemva kwamasonto ayi-6 okuphuza, ukumuncwa kwesikhumba kwathuthuka kakhulu, kwathi ngemva kwamasonto ayi-12, imibimbi kanye nokuqina kwesikhumba kwathuthuka, okubonisa imiphumela yokulwa nokuguga. Imiphumela ibonise ukuthuthuka okukhulu ekugcinweni komswakama wesikhumba ngemva kwamasonto ayi-6 okuphuza kanye nomphumela wokulwa nokuguga ngemva kwamasonto ayi-12.